Dr Christine Zeedrew, at the National Institute for Health, recognised a disturbing pattern between wheat and mental health. She observed that, globally, those treating people with Schizophrenia noticed when their patients were exposed to wheat foods they had hallucinations and heard voices. When wheat was taken out of their diets, the hallucinations stopped.
Dr Zeedrew questioned what it was in wheat that created Schizophrenics to react the way they did. In her bid to find out, she took wheat proteins and put them through the process of digestion. She discovered that when wheat was broken down, during the digestive process, it did so into many small proteins, or polypeptides.
These small proteins, called exoporphins, had the ability to cross the blood-brain barrier (a normally impermeable sheath that covers the brain) and bind themselves to the opiate receptors. This created negative behavioural changes and had the same effect of narcotics but without the pleasurable high.
Another interesting discovery Dr Zeedrew made was that not only did the gliadin negatively affect the personality, it also increased the appetite.
The tests were initially done on mice and then on a group of human volunteers. During the tests, the volunteers were injected with the drug Nalaxone (an opiate blocking drug given to high heroin addicts to automatically reverse the effects of heroin) and were instructed to eat wheat foods. When they ate after having the drug administered, they consumed about seven hundred calories. When the same experiment was done without the injection of Nalaxone, they found the volunteers consumed at least four hundred calories more. Proving that wheat has the effect of making us overeat!